JUSTINE WHEATLEY, RN: That does form a problem to the average person, because generally, most people have a fear of needles. No one wants to have to stick themselves with a needle, let alone be sticked or have to self-inject
ANNOUNCER: There are three different interferons preparations.
JUSTINE WHEATLEY, RN: The three interferons, the Rebif, Betaseron and Avonex, are all injectable medications, Rebif and the Betaseron, both subcutaneous injections, under the skin, so they're given more frequently. They're given every other day or, in the case of Rebif, three times a week.
Avonex is intramuscular, therefore it doesn't have to be given so often. So it's given once a week.
ANNOUNCER: While the pain of the actual needle is minimal, there can be some discomfort afterwards.
JUSTINE WHEATLEY, RN: The most injection site reactions are seen in subcutaneous injection. The medication can be irritative to the tissue, because the tissue is right under the skin. Therefore, you can get heat, redness, swelling, itchiness and even a hardening of the tissue. Intramuscular reaction: there can be muscle soreness.
Reducing side effects can be as minimal as icing the site before you inject; icing the site after you inject; making sure that the medication is room temperature; making sure that you're clean and dry before you begin the injection.
ANNOUNCER: Of course giving yourself a shot doesn't come naturally.
JUSTINE WHEATLEY, RN: Make sure that your nurse or your doctor or whoever's teaching you gives you the hands-on, answers all questions.